Description

(4-Boc-Amino-Piperidin-1-Yl)-Pyridin-4-Yl-Acetic Acid CAS NO 885275-36-5 is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core protected by a tert-butoxycarbonyl (Boc) group. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially kinase inhibitors.
• Protease Inhibitor Research: Used in the development of compounds targeting various protease enzymes.
• Chemical Biology & Probe Development: Serves as a scaffold for creating molecular probes to study biological pathways.
• Peptidomimetic Synthesis: Integral for constructing non-peptide compounds that mimic peptide structures for enhanced stability and bioavailability.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	(4-Boc-Amino-Piperidin-1-Yl)-Pyridin-4-Yl-Acetic Acid
CAS No.	885275-36-5
Molecular Formula	C17H25N3O4
Molecular Weight	335.40 g/mol
Synonyms	1-(4-Pyridinylacetyl)-4-[(1,1-dimethylethoxy)carbonyl]amino]piperidine; 4-[(tert-Butoxycarbonyl)amino]-1-(4-pyridin-4-ylacetyl)piperidine; 4-(Boc-amino)-1-(pyridin-4-ylacetyl)piperidine; 4-(N-Boc-amino)piperidin-1-yl-pyridin-4-yl-acetic acid; N-Boc-4-amino-1-(4-pyridylacetyl)piperidine; (4-{[(tert-Butoxycarbonyl)amino]methyl}piperidin-1-yl)(pyridin-4-yl)acetic acid (related isomer); Boc-4-Amino-Pip-4-PyAcOH
EINECS	Contact for details

Quality Control

Our (4-Boc-Amino-Piperidin-1-Yl)-Pyridin-4-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and development standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.