Description

2-(4-n-Fmoc-Morpholin-2-Yl)Acetic Acid is a high-purity, protected amino acid derivative designed for advanced organic synthesis. This compound is a critical building block in the synthesis of complex molecules, particularly in the field of peptide and medicinal chemistry, where it enables the precise introduction of a morpholine moiety. It is primarily utilized by research institutions and pharmaceutical companies for drug discovery, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: A key intermediate for the solid-phase and solution-phase synthesis of peptides containing morpholine-based unnatural amino acids.
• Pharmaceutical Research: Serves as a crucial building block in medicinal chemistry for the development of novel drug candidates, particularly protease inhibitors and receptor modulators.
• Chemical Biology: Used in the synthesis of labeled probes and molecular tools for studying biological pathways and protein-protein interactions.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex organic molecules in pilot plant and manufacturing settings.
• Library Synthesis: A valuable reagent for generating diverse compound libraries in high-throughput screening campaigns for drug discovery.

Basic Information

Product Name	2-(4-n-Fmoc-Morpholin-2-Yl)Acetic Acid
CAS No.	885273-97-2
Molecular Formula	C21H21NO6
Molecular Weight	383.40 g/mol
Synonyms	2-[(4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}morpholin-2-yl)]acetic Acid; Fmoc-Morpholine-2-acetic Acid; 2-(4-Fmoc-Aminomorpholin-2-yl)acetic Acid; N-Fmoc-2-morpholineacetic Acid; 2-(4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)morpholin-2-yl)acetic Acid; 885273-97-2; Fmoc-protected morpholine acetic acid derivative.
EINECS	Contact for details

Quality Control

Our 2-(4-n-Fmoc-Morpholin-2-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural integrity suitable for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.