Description

8-Chloro-2H-isothiazolo[5,4-b]quinolizine-3,4-dione is a specialized heterocyclic organic compound featuring a fused isothiazoloquinolizine-dione core structure. This compound matters as a high-value chemical intermediate and pharmacophore for advanced research and development in medicinal chemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides with novel modes of action.
• Chemical Biology Probe: Serves as a core scaffold for creating molecular probes to study enzyme function or protein-protein interactions in biological systems.
• Material Science Precursor: Potential intermediate for the synthesis of organic electronic materials or dyes with specific photophysical properties.
• Academic & Institutional R&D: Utilized in university and government laboratories for fundamental research in heterocyclic and synthetic organic chemistry.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for complex molecules in pilot plants.

Basic Information

Item	Details
Product Name	8-Chloro-2H-isothiazolo[5,4-b]quinolizine-3,4-dione
CAS No.	885272-29-7
Molecular Formula	C₁₂H₅ClN₂O₂S
Molecular Weight	276.70 g/mol
Synonyms	8-Chloro-2H-[1,2]thiazolo[5,4-b]quinolizine-3,4-dione; 8-Chloro-2H-[1,2]thiazolo[5,4-b]quinolizine-3,4-dione; 885272-29-7; 8-Chloro-2H-isothiazolo[5,4-b]quinolizine-3,4-dione; 8-Chloro-2H-[1,2]thiazolo[5,4-b]quinolizine-3,4(5H)-dione; SCHEMBL21833027; AKOS040759623; ZINC000103014511
EINECS	Contact for details

Quality Control

Our 8-Chloro-2H-isothiazolo[5,4-b]quinolizine-3,4-dione is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing results from HPLC, NMR, and MS analyses. Our commitment to reliable supply and documentation integrity supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to atmospheric moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.