Description

Methyl 3-Oxo-7-(Trifluoromethyl)-3,4-Dihydroquinoxaline-2-Carboxylate is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core quinoxaline scaffold, functionalized with a trifluoromethyl group and a methyl ester, makes it a versatile intermediate for creating novel compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Material Science: Acts as a building block for creating specialized organic electronic materials, such as charge-transport layers or fluorinated polymers.
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Custom Synthesis: Provided to contract research organizations (CROs) and custom synthesis manufacturers for client-specific research projects and scale-up development.

Basic Information

Product Name	Methyl 3-Oxo-7-(Trifluoromethyl)-3,4-Dihydroquinoxaline-2-Carboxylate
CAS No.	885271-85-2
Molecular Formula	C11H7F3N2O3
Molecular Weight	272.18 g/mol
Synonyms	Methyl 7-(trifluoromethyl)-3-oxo-3,4-dihydroquinoxaline-2-carboxylate; 2-Quinoxalinecarboxylic acid, 3,4-dihydro-3-oxo-7-(trifluoromethyl)-, methyl ester; 7-(Trifluoromethyl)-3,4-dihydro-3-oxoquinoxaline-2-carboxylic acid methyl ester; Methyl 3-keto-7-trifluoromethyl-3,4-dihydroquinoxaline-2-carboxylate; 3-Oxo-7-(trifluoromethyl)-3,4-dihydro-2-quinoxalinecarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Oxo-7-(Trifluoromethyl)-3,4-Dihydroquinoxaline-2-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable and can support regulatory filings with necessary documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.