Description

2-Amino-6-(Trifluoromethyl)-4H-Benzo[D][1,3]Oxazin-4-One is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the 1,3-oxazin-4-one scaffold and the electron-withdrawing trifluoromethyl group, which is crucial for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the CF3 group.
• Material Science: Used in the research of advanced organic materials, such as liquid crystals or organic semiconductors, where fluorination improves stability and performance.
• Chemical Biology: Employed as a probe or labeling agent in biochemical studies due to its reactive amino and carbonyl functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for the production of bespoke compounds and complex molecules on a commercial scale.

Basic Information

Product Name	2-Amino-6-(Trifluoromethyl)-4H-Benzo[D][1,3]Oxazin-4-One
CAS No.	885271-61-4
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	2-Amino-6-(trifluoromethyl)-4H-3,1-benzoxazin-4-one; 6-(Trifluoromethyl)-2-amino-4H-benzo[d][1,3]oxazin-4-one; 2-Amino-6-trifluoromethyl-4H-benzo[d][1,3]oxazin-4-one; 4H-3,1-Benzoxazin-4-one, 2-amino-6-(trifluoromethyl)-; 885271-61-4; Benzoxazinone derivative, CF3-substituted
EINECS	Contact for details

Quality Control

Our 2-Amino-6-(Trifluoromethyl)-4H-Benzo[D][1,3]Oxazin-4-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.