Description

8-Bromo-6-Chloro-2H-Chromene-3-Carboxylic Acid is a high-purity, halogenated chromene derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its unique molecular scaffold, which enables the construction of complex heterocyclic systems with potential biological activity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry programs and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly for exploring chromene-based pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its modifiable bromo and chloro substituents.
• Agrochemical Development: Serves as a precursor in the creation of new pesticides or herbicides where the chromene core is investigated for biological efficacy.
• Chemical Synthesis: Employed in organic synthesis for constructing fused heterocyclic compounds and in cross-coupling reactions facilitated by the bromine atom.
• Material Science Research: Potential use as a monomer or precursor in the development of specialized organic materials and polymers.

Basic Information

Product Name	8-Bromo-6-Chloro-2H-Chromene-3-Carboxylic Acid
CAS No.	885271-01-2
Molecular Formula	C10H6BrClO3
Molecular Weight	289.51 g/mol
Synonyms	8-Bromo-6-chloro-2H-1-benzopyran-3-carboxylic acid; 6-Chloro-8-bromo-2H-chromene-3-carboxylic acid; 8-Bromo-6-chloro-3-carboxy-2H-chromene; 885271-01-2; 2H-1-Benzopyran-3-carboxylic acid, 8-bromo-6-chloro-; 6-Chloro-8-bromochromene-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Chloro-2H-Chromene-3-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.