Description

3-(3-Fluorophenylsulfonamido)Benzoic Acid is a high-purity, specialized organic intermediate featuring a benzoic acid core linked to a fluorinated phenylsulfonamide group. This compound is valued for its role as a critical building block in advanced pharmaceutical and agrochemical research, enabling the synthesis of novel active ingredients. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for creating compounds with targeted biological activity. The structural motif offers potential for modulating pharmacokinetic properties in drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, or insecticides, where the fluorine atom and sulfonamide group can enhance bioactivity and environmental stability.
• Chemical Biology Probe Development: Used to create tool compounds and molecular probes for studying enzyme function and biological pathways in academic and industrial research settings.
• Material Science Precursor: Potential building block for advanced polymers or functional materials requiring specific aromatic and fluorinated components for tailored properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	3-(3-Fluorophenylsulfonamido)Benzoic Acid
CAS No.	885269-80-7
Molecular Formula	C13H10FNO4S
Molecular Weight	295.29 g/mol
Synonyms	3-[(3-Fluorophenyl)sulfamoyl]benzoic acid; Benzoic acid, 3-[(3-fluorophenyl)sulfamoyl]-; 3-(3-Fluorobenzenesulfonamido)benzoic acid; 3-(3-Fluorophenylsulfonylamino)benzoic acid; 3-(3-Fluoro-N-phenylsulfonamido)benzoic acid; 3-(3-Fluorophenylsulfonamido)benzoate; FPSA; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Fluorophenylsulfonamido)Benzoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (HPLC), with options for higher purities (≥98%, ≥99%) available for advanced research applications. Certificates of Analysis (COA) detailing batch-specific results for assay, related substances, and residual solvents are provided with each shipment. We support cGMP-compliant documentation for pharmaceutical development projects upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0% Any single impurity ≤1.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.