Description

6'-Bromo-2',3'-Dihydro-1'H-Spiro[Cyclopentane-1,4'-Isoquinoline] is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) with complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the spiro[cyclopentane-isoquinoline] moiety into target molecules.
• Contract Research & Development (CRO/CDMO): Supplied to organizations specializing in custom synthesis and process optimization for client projects.
• Academic Research: Utilized in university and institutional labs for methodological development and the study of spirocyclic compound chemistry.

Basic Information

Product Name	6'-Bromo-2',3'-Dihydro-1'H-Spiro[Cyclopentane-1,4'-Isoquinoline]
CAS No.	885269-45-4
Molecular Formula	C₁₃H₁₄BrN
Molecular Weight	264.16 g/mol
Synonyms	6'-Bromo-2',3'-dihydro-1'H-spiro[cyclopentane-1,4'-isoquinoline]; 6'-Bromospiro[cyclopentane-1,4'-isoquinoline]; 1'H-Spiro[cyclopentane-1,4'-isoquinoline], 6'-bromo-2',3'-dihydro-; Spiro[cyclopentane-1,4'-isoquinoline], 6'-bromo-2',3'-dihydro-1'H-; 885269-45-4; 6-Bromo-2,3-dihydro-1H-spiro[cyclopentane-1,4-isoquinoline]; 6'-Bromo-1'H-spiro[cyclopentane-1,4'-isoquinoline]-2',3'-dihydro
EINECS	Contact for details

Quality Control

Every batch of 6'-Bromo-2',3'-Dihydro-1'H-Spiro[Cyclopentane-1,4'-Isoquinoline] is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.