Description

2-(4-Bromophenyl)-5-Fluoroindole is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated indole structure. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS therapeutic areas. It is primarily utilized by R&D chemists and process development scientists in pharmaceutical and biotechnology companies for lead optimization and scale-up synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potent kinase inhibitors and other targeted small-molecule therapeutics.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead compound optimization due to its bromophenyl and fluoroindole motifs.
• Chemical Reference Standard: Serves as an analytical standard for quality control and method development in API manufacturing.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex molecular architectures.
• Biochemical Tool Compound: Used in vitro to study biological pathways and protein-ligand interactions.

Basic Information

Product Name	2-(4-Bromophenyl)-5-Fluoroindole
CAS No.	885266-74-0
Molecular Formula	C14H9BrFN
Molecular Weight	290.13 g/mol
Synonyms	5-Fluoro-2-(4-bromophenyl)indole; 2-(4-Bromophenyl)-5-fluoro-1H-indole; 1H-Indole, 5-fluoro-2-(4-bromophenyl)-; 5-Fluoro-2-(p-bromophenyl)indole; 2-(p-Bromophenyl)-5-fluoroindole; 5-Fluoro-2-(4'-bromophenyl)indole; 2-(4-Bromophenyl)-5-fluoroindole
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-5-Fluoroindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.