Description

3-Iodo-6-(2-(Methylcarbamoyl)Phenylthio)-1H-1-Boc-Indazole is a sophisticated, high-purity chemical intermediate designed for advanced pharmaceutical research and development. This compound is valued for its role as a key building block in the synthesis of novel therapeutic agents, particularly in targeted drug discovery programs. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for creating potential drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex small-molecule drug candidates, especially those targeting specific enzymes or receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Protease Inhibitor Development: Used in the research and development of potential protease inhibitors, given its indazole-thioether core structure.
• Kinase Inhibitor Synthesis: Employed as a building block for creating novel kinase inhibitor libraries for oncology and inflammatory disease research.
• Chemical Biology Probes: Utilized in the development of chemical probes to study biological pathways and protein function.
• Process Chemistry: Serves as an intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-Iodo-6-(2-(Methylcarbamoyl)Phenylthio)-1H-1-Boc-Indazole
CAS No.	885126-37-4
Molecular Formula	C20H20IN3O3S
Molecular Weight	509.36 g/mol
Synonyms	1H-Indazole, 3-iodo-6-[[2-[(methylamino)carbonyl]phenyl]thio]-, 1-(1,1-dimethylethyl) ester; tert-Butyl 3-iodo-6-((2-(methylcarbamoyl)phenyl)thio)-1H-indazole-1-carboxylate; 1-Boc-3-iodo-6-(2-(methylcarbamoyl)phenylthio)indazole; Boc-Protected 3-Iodo-6-thioindazole derivative; 885126-37-4; 3-Iodo-6-(2-(methylcarbamoyl)phenylthio)-1H-indazole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-Iodo-6-(2-(Methylcarbamoyl)Phenylthio)-1H-1-Boc-Indazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support pre-clinical and clinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.