Description

7-Chloro-4-Isothiocyanatoquinoline is a versatile and highly functionalized quinoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the reactive isothiocyanate group, which enables efficient conjugation and derivatization for creating novel molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialized chemical probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates with potential antimicrobial, anticancer, or antimalarial activity.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the quinoline core.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling, modifying, or cross-linking biomolecules like proteins and peptides due to the isothiocyanate functionality.
• Material Science: Building block for creating functionalized polymers, ligands for metal-organic frameworks (MOFs), or advanced organic electronic materials.
• Dye & Pigment Synthesis: Intermediate for producing specialized heterocyclic dyes and fluorescent markers.
• Academic & Contract Research: Serves as a valuable reagent for methodological development and discovery chemistry in research laboratories.

Basic Information

Product Name	7-Chloro-4-Isothiocyanatoquinoline
CAS No.	884647-32-9
Molecular Formula	C10H5ClN2S
Molecular Weight	220.68 g/mol
Synonyms	4-Isothiocyanato-7-chloroquinoline; 7-Chloro-4-isothiocyanato-quinoline; Quinoline, 7-chloro-4-isothiocyanato-; 7-Chloro-4-quinoline isothiocyanate
EINECS	Contact for details

Quality Control

Our 7-Chloro-4-Isothiocyanatoquinoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, the container should be amber-colored or kept in opaque secondary packaging. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.