Description

6-Amino-5-Bromo-3,4-Dihydronaphthalen-1(2H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused-ring structure containing both amino and bromo functional groups. This compound is a critical building block in the synthesis of complex organic molecules, particularly in medicinal chemistry for the development of new active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where its specific substitution pattern enables precise molecular modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing polycyclic frameworks via reactions such as palladium-catalyzed cross-coupling, cyclization, and functional group transformations.
• Agrochemical Research: Serves as a starting material for developing novel active ingredients in crop protection products, leveraging its halogenated aromatic structure.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors, dyes, and photoactive materials due to its conjugated dihydronaphthalenone core.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	6-Amino-5-Bromo-3,4-Dihydronaphthalen-1(2H)-One
CAS No.	884541-34-8
Molecular Formula	C10H10BrNO
Molecular Weight	240.10 g/mol
Synonyms	5-Bromo-6-amino-3,4-dihydronaphthalen-1(2H)-one; 1(2H)-Naphthalenone, 6-amino-5-bromo-3,4-dihydro-; 6-Amino-5-bromo-1-tetralone; 5-Bromo-6-amino-α-tetralone; 6-Amino-5-bromo-3,4-dihydro-1(2H)-naphthalenone; 5-Bromo-6-amino-3,4-dihydro-2H-naphthalen-1-one
EINECS	Contact for details

Quality Control

Our 6-Amino-5-Bromo-3,4-Dihydronaphthalen-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.