Description

1,5-Naphthyridine-2-Carboxaldehyde is a versatile and high-purity organic building block characterized by its reactive aldehyde functional group fused to a 1,5-naphthyridine heterocyclic core. This compound is of significant value in advanced organic synthesis and pharmaceutical research, serving as a key precursor for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry and ligand synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic scaffold.
• Ligand Synthesis: Serves as a starting material for creating sophisticated chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials and fluorescent dyes due to its conjugated system.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory chemistry in university and CRO laboratories.
• Chemical Library Production: Used in high-throughput and combinatorial chemistry to generate diverse compound libraries for screening.

Basic Information

Product Name	1,5-Naphthyridine-2-Carboxaldehyde
CAS No.	883864-92-4
Molecular Formula	C9H6N2O
Molecular Weight	158.16 g/mol
Synonyms	1,5-Naphthyridine-2-carbaldehyde; 2-Formyl-1,5-naphthyridine; 1,5-Naphthyridine-2-carboxaldehyde; 1,5-Naphthyridine-2-carbaldehyde; 2-(1,5-Naphthyridinyl)carboxaldehyde; 883864-92-4; 1,5-Naphthyridine-2-carboxylic aldehyde
EINECS	Contact for details

Quality Control

Our 1,5-Naphthyridine-2-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.