Description

6',7'-Dichloro-1',2'-Dihydrospiro([1,3]Dioxane-2,3'-Indole)-2'-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic indole-dioxane structure. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile and functionalized scaffold for medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
• Organic Synthesis: Employed in the construction of complex heterocyclic systems due to its reactive functional groups and rigid spirocyclic framework.
• Reference Standard: Utilized as an analytical standard for quality control and method development in laboratories producing or researching related compounds.
• Biochemical Tool Compound: Potential use in biochemical assays to study biological mechanisms and identify new therapeutic targets.

Basic Information

Product Name	6',7'-Dichloro-1',2'-Dihydrospiro([1,3]Dioxane-2,3'-Indole)-2'-One
CAS No.	883647-79-8
Molecular Formula	C12H9Cl2NO3
Molecular Weight	286.11 g/mol
Synonyms	6',7'-Dichloro-1',2'-dihydrospiro[1,3-dioxane-2,3'-indol]-2'-one; Spiro[1,3-dioxane-2,3'-indole]-2'-one, 6',7'-dichloro-1',2'-dihydro-; 6,7-Dichloro-1,2-dihydrospiro[1,3-dioxane-2,3'-indole]-2'-one; 6',7'-Dichloro-1',2'-dihydrospiro(1,3-dioxane-2,3'-indole)-2'-one; CAS 883647-79-8
EINECS	Contact for details

Quality Control

Our 6',7'-Dichloro-1',2'-Dihydrospiro([1,3]Dioxane-2,3'-Indole)-2'-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.