Description

1-(1-Cyclohexyl-3-Piperidinyl)Methanamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic amine structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• CNS Drug Discovery: Used in the synthesis of compounds targeting neurological receptors and pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry & Scale-Up: Employed in route scouting and the development of robust, scalable synthetic processes for API manufacturing.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	1-(1-Cyclohexyl-3-Piperidinyl)Methanamine Dihydrochloride
CAS No.	883533-78-6
Molecular Formula	C12H24N2·2HCl
Molecular Weight	269.25 g/mol (as free base: 196.33 g/mol)
Synonyms	1-(1-Cyclohexyl-3-piperidinyl)methanamine dihydrochloride; 1-(1-Cyclohexylpiperidin-3-yl)methanamine hydrochloride (1:2); N-[(1-Cyclohexyl-3-piperidinyl)methyl]amine dihydrochloride; 1-Cyclohexyl-3-(aminomethyl)piperidine dihydrochloride; 1-(Aminomethyl)-1-cyclohexyl-3-piperidine dihydrochloride; 883533-78-6 (CAS); 1-(1-Cyclohexylpiperidin-3-yl)methanamine 2HCl
EINECS	Contact for details

Quality Control

Our 1-(1-Cyclohexyl-3-Piperidinyl)Methanamine Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.