Description

1-(1-Cyclopentyl-3-Piperidinyl)Methanamine (2HCl) is a high-purity, advanced pharmaceutical intermediate with a defined stereochemical structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the central nervous system (CNS) and metabolic disorder spaces. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting G-protein-coupled receptors (GPCRs).
• Neurological Research: Used in the development of potential treatments for disorders such as Parkinson's disease, schizophrenia, and depression.
• Metabolic Disorder Research: Serves as a precursor in compounds being studied for diabetes and obesity management.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	1-(1-Cyclopentyl-3-Piperidinyl)Methanamine (2HCl)
CAS No.	883521-63-9
Molecular Formula	C11H22N2 • 2HCl
Molecular Weight	267.23 g/mol (Free base: 182.31 g/mol)
Synonyms	1-(1-Cyclopentylpiperidin-3-yl)methanamine dihydrochloride; 1-(1-Cyclopentyl-3-piperidinyl)methanamine hydrochloride (1:2); 1-(Cyclopentylpiperidin-3-yl)methanamine dihydrochloride; 3-(Aminomethyl)-1-cyclopentylpiperidine dihydrochloride; 1-Cyclopentyl-3-(aminomethyl)piperidine dihydrochloride; (1-Cyclopentylpiperidin-3-yl)methanamine dihydrochloride; 1-Cyclopentyl-3-piperidinemethanamine dihydrochloride
EINECS	Contact for details

Quality Control

Our production of 1-(1-Cyclopentyl-3-Piperidinyl)Methanamine (2HCl) adheres to stringent quality management systems. Each batch is manufactured under controlled conditions and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.