Description

2-Cyano-4,5-Diaminobenzotrifluoride, also known as 4-Cyano-5-(Trifluoromethyl)Benzene-1,2-Diamine, is a high-value, multi-functional aromatic intermediate featuring both cyano and diamine functional groups on a trifluoromethyl-substituted benzene ring. This unique structure makes it a critical building block for synthesizing advanced materials and active pharmaceutical ingredients (APIs) that require specific electronic and steric properties. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with enhanced bioactivity and stability.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies where the trifluoromethyl and cyano groups modulate potency and metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its structural motifs to improve efficacy and environmental profile.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the production of high-performance polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Integral to creating specialized dyes and pigments, where the diamine group facilitates coupling reactions and the cyano/trifluoromethyl groups influence color and lightfastness.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science research, enabling the exploration of new chemical spaces.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated ligands for transition metal catalysts employed in fine chemical and pharmaceutical manufacturing.

Basic Information

Product Name	2-Cyano-4,5-Diaminobenzotrifluoride, 4-Cyano-5-(Trifluoromethyl)Benzene-1,2-Diamine
CAS No.	882978-62-3
Molecular Formula	C8H5F3N3
Molecular Weight	200.14 g/mol
Synonyms	4-Cyano-5-(trifluoromethyl)-1,2-benzenediamine; 1,2-Benzenediamine, 4-cyano-5-(trifluoromethyl)-; 2-Cyano-4,5-diaminobenzotrifluoride; 5-(Trifluoromethyl)-4-cyano-1,2-phenylenediamine; 4,5-Diamino-2-cyanobenzotrifluoride; 2-Amino-4-cyano-5-(trifluoromethyl)aniline; 4-Cyano-5-trifluoromethylbenzene-1,2-diamine
EINECS	Contact for details

Quality Control

Every batch of 2-Cyano-4,5-Diaminobenzotrifluoride is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical and advanced material applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.