Description

3-(Fmoc-4-Aminophenyl)-Propionic Acid is a high-purity, protected amino acid derivative designed for advanced organic synthesis. This compound is a critical building block in the solid-phase synthesis of peptides and peptidomimetics, offering precise control over molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the development of novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected intermediate for the controlled, sequential addition of amino acids.
• Peptidomimetic & Drug Discovery: For constructing non-natural peptide backbones and libraries for high-throughput screening.
• Linker Molecule in Bioconjugation: Used to create cleavable or stable linkages between peptides, proteins, and other molecules or surfaces.
• Combinatorial Chemistry: A versatile scaffold for generating diverse chemical libraries.
• Research & Development: Fundamental reagent in academic and industrial R&D for studying protein-protein interactions and signal transduction pathways.
• API Intermediate: Serves as a sophisticated precursor in the synthesis of complex Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	3-(Fmoc-4-Aminophenyl)-Propionic Acid
CAS No.	882847-07-6
Molecular Formula	C24H21NO4
Molecular Weight	387.43 g/mol
Synonyms	Fmoc-4-Aminophenylpropionic Acid; 4-[(9H-Fluoren-9-ylmethoxy)carbonylamino]benzenepropanoic Acid; 3-[4-[(9H-Fluoren-9-ylmethoxycarbonyl)amino]phenyl]propanoic Acid; N-α-Fmoc-4-aminophenylpropionic Acid; Fmoc-Ppa-OH; Fmoc-4-Abz-OH; Fmoc-4-Aminohydrocinnamic Acid; N-Fmoc-4-aminophenylpropionic Acid
EINECS	Contact for details

Quality Control

Our 3-(Fmoc-4-Aminophenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF for moisture content, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.