Description

4-(Methylamino)-3-Nitro-1,5-Naphthyridin-2(1H)-One is a specialized naphthyridine derivative, a high-value chemical intermediate prized for its unique heterocyclic structure. This compound is critical for advanced research and development in pharmaceutical chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of potential drug candidates, especially those targeting kinase inhibition or other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the naphthyridine core offers specific biological activity.
• Organic Synthesis: Acts as a versatile precursor for further chemical modifications, including reduction of the nitro group or functionalization of the methylamino group.
• Material Science Research: Investigated for use in creating organic electronic materials or ligands for metal-organic frameworks (MOFs) due to its electron-deficient aromatic system.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental studies in heterocyclic chemistry and medicinal chemistry.

Basic Information

Product Name	4-(Methylamino)-3-Nitro-1,5-Naphthyridin-2(1H)-One
CAS No.	882651-36-7
Molecular Formula	C10H8N4O3
Molecular Weight	232.20 g/mol
Synonyms	3-Nitro-4-(methylamino)-1,5-naphthyridin-2(1H)-one; 4-(Methylamino)-3-nitro-1,5-naphthyridin-2-ol; 2H-1,5-Naphthyridin-2-one, 4-(methylamino)-3-nitro-; 882651-36-7; 4-Methylamino-3-nitro-1,5-naphthyridin-2(1H)-one; 3-Nitro-4-methylamino-1,5-naphthyridin-2(1H)-one; 4-(Methylamino)-3-nitro-1,5-naphthyridin-2-ol (tautomer)
EINECS	Contact for details

Quality Control

Our 4-(Methylamino)-3-Nitro-1,5-Naphthyridin-2(1H)-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or development specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original container. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.