Description

6-Bromo-4-Methoxy-2-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, which combines bromo, methoxy, and trifluoromethyl substituents on a quinoline core, enabling precise structural modifications in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and anti-cancer compounds.
• Agrochemical Research: Used in the synthesis of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport layers.
• Fluorescent Probe Synthesis: The quinoline scaffold is utilized to create specialized fluorescent dyes and sensors for biochemical imaging and diagnostics.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and library synthesis in medicinal chemistry.

Basic Information

Item	Details
Product Name	6-Bromo-4-Methoxy-2-(Trifluoromethyl)Quinoline
CAS No.	882292-61-7
Molecular Formula	C₁₁H₇BrF₃NO
Molecular Weight	306.08 g/mol
Synonyms	6-Bromo-4-methoxy-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-6-bromo-4-methoxyquinoline; 4-Methoxy-6-bromo-2-trifluoromethylquinoline; Quinoline, 6-bromo-4-methoxy-2-(trifluoromethyl)-; 882292-61-7; 6-Bromo-4-methoxy-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Methoxy-2-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.