Description

1-Methyl-Spiro[3H-Indole-3,2'-[2H]Pyran]-2,6'(1H,3'H)-Dione is a high-purity, complex heterocyclic compound featuring a unique spiro-fused indole-pyran structure, making it a valuable synthetic intermediate and building block for advanced research. This compound is critical for applications requiring precise molecular architecture, such as in the development of novel pharmaceuticals and functional materials. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic cores.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its unique spirocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic electronic materials, dyes, and pigments due to its conjugated indole-based system.
• Academic & R&D: Employed in methodological chemistry research for studying spiroannulation reactions and developing new synthetic pathways.
• Chemical Biology: Utilized as a probe or scaffold in the design of enzyme inhibitors or molecular probes for biological studies.

Basic Information

Product Name	1-Methyl-Spiro[3H-Indole-3,2'-[2H]Pyran]-2,6'(1H,3'H)-Dione
CAS No.	882041-46-5
Molecular Formula	C13H11NO3
Molecular Weight	229.23 g/mol
Synonyms	1-Methylspiro[indole-3,2'-pyran]-2,6'-dione; 1-Methyl-1'H-spiro[indole-3,2'-pyran]-2,6'-dione; 1-Methyl-1'H-spiro[indole-3,2'-[2H]pyran]-2,6'-dione; 1-Methyl-2,6-dioxo-1,3-dihydrospiro[indole-3,2'-2H-pyran]; Spiro[1-methyl-1H-indole-3,2'-[2H]pyran]-2,6'(3'H)-dione; 882041-46-5; 1-Methylspiro[indoline-3,2'-pyran]-2,6'-dione (tautomer form)
EINECS	Contact for details

Quality Control

Our 1-Methyl-Spiro[3H-Indole-3,2'-[2H]Pyran]-2,6'(1H,3'H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.