Description

2-Oxo-1,2,3,4-Tetrahydroquinoline-5-Carbonitrile is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core quinoline-2-one scaffold functionalized with a nitrile group makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, dyes, and pigments due to its conjugated system and functional handles.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing fused polycyclic compounds and exploring novel chemical reactions.
• Ligand and Catalyst Development: The nitrogen and oxygen atoms in its structure can be utilized to create novel ligands for metal catalysis.

Basic Information

Product Name	2-Oxo-1,2,3,4-Tetrahydroquinoline-5-Carbonitrile
CAS No.	882023-24-7
Molecular Formula	C10H8N2O
Molecular Weight	172.18 g/mol
Synonyms	5-Cyano-3,4-dihydro-2(1H)-quinolinone; 5-Cyano-1,2,3,4-tetrahydroquinolin-2-one; 1,2,3,4-Tetrahydro-2-oxoquinoline-5-carbonitrile; 2-Oxo-1,2,3,4-tetrahydroquinoline-5-carbonitrile; Quinoline-5-carbonitrile, 1,2,3,4-tetrahydro-2-oxo-; 5-CN-THQ; A-933858
EINECS	Contact for details

Quality Control

Our 2-Oxo-1,2,3,4-Tetrahydroquinoline-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.