Description

(S)-n-Boc-2-Furylalanine tert-Butylamine is a high-purity, non-natural amino acid derivative featuring a chiral center and a furan-protected side chain. This compound is a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, particularly peptidomimetics and protease inhibitors. It is essential for research and development chemists in the pharmaceutical, biotechnology, and fine chemical sectors who require high-quality, enantiomerically pure intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of protease inhibitors and other therapeutic peptides.
• Peptidomimetic Research: Used in medicinal chemistry to create stable, bioavailable analogs of natural peptides for drug discovery programs.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in stereoselective organic synthesis to introduce the (S)-2-amino-3-(2-furyl)propanoic acid moiety.
• Bioconjugation & Labeling: The tert-butylamine salt form and Boc-protected amine offer orthogonal protection strategies for complex multi-step syntheses and bioconjugation chemistry.
• Academic & Industrial R&D: A valuable reagent for research laboratories focused on developing new synthetic methodologies and exploring structure-activity relationships (SAR).

Basic Information

Product Name	(S)-n-Boc-2-Furylalanine tert-Butylamine
CAS No.	881690-67-1
Molecular Formula	C₁₆H₂₆N₂O₅
Molecular Weight	326.39 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-3-(furan-2-yl)propanoic acid tert-butylamine salt; (S)-N-Boc-2-Furylalanine tert-Butylamine; (S)-3-(2-Furyl)-N-[(1,1-dimethylethoxy)carbonyl]alanine tert-butylamine; Boc-L-2-Furylalanine tert-Butylamine salt; (S)-N-(tert-Butoxycarbonyl)-2-furylalanine tert-butylamine; L-N-Boc-2-Furylalanine tert-butylamine; tert-Butyl (S)-2-amino-3-(furan-2-yl)propanoate tert-butylamine salt
EINECS	Contact for details

Quality Control

Our (S)-n-Boc-2-Furylalanine tert-Butylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity, to ensure compliance with high-purity standards typical for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.