Description

8-Bromo-2-Methoxy-1,5-Naphthyridine is a high-purity, functionalized naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures through selective cross-coupling and functional group transformations. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Synthesis: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the naphthyridine scaffold into more complex molecules.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	8-Bromo-2-Methoxy-1,5-Naphthyridine
CAS No.	881658-92-0
Molecular Formula	C9H7BrN2O
Molecular Weight	239.07 g/mol
Synonyms	8-Bromo-2-methoxy-1,5-naphthyridine; 2-Methoxy-8-bromo-1,5-naphthyridine; 1,5-Naphthyridine, 8-bromo-2-methoxy-; 881658-92-0; 8-Br-2-MeO-1,5-Naphthyridine
EINECS	Contact for details

Quality Control

Our 8-Bromo-2-Methoxy-1,5-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.