Description

4-Quinolinemethanol, 5,6,7,8-Tetrahydro--α--Methyl--α--[1-(Triphenylmethyl)-1H-Imidazol-4-Yl]- is a sophisticated heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical research and development. Its complex molecular architecture, featuring fused quinoline and imidazole rings with a trityl-protecting group, makes it a valuable building block for medicinal chemists. This compound is primarily utilized in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas, where high-purity intermediates are essential for successful outcomes.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for CNS-targeting drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery programs.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study enzyme function and biological pathways.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial drug production.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs specializing in complex, multi-step organic synthesis.
• Academic Research: Used in university and institutional laboratories for the development of new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	4-Quinolinemethanol, 5,6,7,8-Tetrahydro--α--Methyl--α--[1-(Triphenylmethyl)-1H-Imidazol-4-Yl]-
CAS No.	880652-90-4
Molecular Formula	C34H31N3O
Molecular Weight	497.63 g/mol
Synonyms	α-Methyl-α-[1-(triphenylmethyl)-1H-imidazol-4-yl]-5,6,7,8-tetrahydro-4-quinolinemethanol; 5,6,7,8-Tetrahydro-α-methyl-α-[1-(triphenylmethyl)-1H-imidazol-4-yl]-4-quinolinemethanol; 4-Quinolinemethanol, 5,6,7,8-tetrahydro-α-methyl-α-[1-(triphenylmethyl)-1H-imidazol-4-yl]-; (4-Quinolinyl)methanol derivative with trityl-protected imidazole; Trityl-Imidazole-Quinoline Methanol Derivative; CAS 880652-90-4
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under strict quality management systems to ensure consistency and reliability for critical research applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and GMP-like environments, ensuring the material's integrity throughout the supply chain.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.