Description

5-(2-Hydroxyethyl)-3-(2-Hydroxyphenyl)-4-(4-Methoxyphenyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(2H)-one is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolone class of heterocyclic compounds. Its complex molecular architecture makes it a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and biotechnology sectors, particularly those focused on central nervous system (CNS) agents and anti-inflammatory drugs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Development: Integral in the process development and optimization for new Active Pharmaceutical Ingredients, particularly in the pyrazolo-pyrrolidine chemical space.
• Biochemical Research: May be utilized as a tool compound or inhibitor in enzymatic assays and biochemical studies due to its specific heterocyclic structure.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and clinical trial material production.
• Academic Research: Used in university and institutional labs for advanced organic synthesis methodology development and heterocyclic chemistry exploration.

Basic Information

Item	Details
Product Name	5-(2-Hydroxyethyl)-3-(2-Hydroxyphenyl)-4-(4-Methoxyphenyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(2H)-one
CAS No.	880394-80-9
Molecular Formula	C22H21N3O4
Molecular Weight	391.42 g/mol
Synonyms	5-(2-Hydroxyethyl)-3-(2-hydroxyphenyl)-4-(4-methoxyphenyl)-4,5-dihydro-2H-pyrrolo[3,4-c]pyrazol-6-one; 4,5-Dihydro-6H-pyrrolo[3,4-c]pyrazol-6-one, 5-(2-hydroxyethyl)-3-(2-hydroxyphenyl)-4-(4-methoxyphenyl)-; Fused pyrazolone derivative; Pyrazolo-pyrrolidine intermediate; CAS 880394-80-9
EINECS	Contact for details

Quality Control

Our 5-(2-Hydroxyethyl)-3-(2-Hydroxyphenyl)-4-(4-Methoxyphenyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(2H)-one is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.