Description

Benzenepropanoic Acid, 4-Ethynyl- is a specialized aromatic compound featuring a propanoic acid backbone and a terminal ethynyl group, making it a valuable building block in advanced organic synthesis. Its unique structure provides a reactive handle for click chemistry and other coupling reactions, enabling the construction of complex molecular architectures. This intermediate is primarily sought by research institutions and pharmaceutical companies for applications in medicinal chemistry, materials science, and the development of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Organic Synthesis Building Block: Utilized in coupling reactions (e.g., Sonogashira, Huisgen cycloaddition) to introduce aromatic and alkyne functionalities into target molecules.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Materials Science Research: Employed in the synthesis of novel polymers, dendrimers, and organic electronic materials due to its conjugated system.
• Chemical Biology Probes: Used to create tagged molecules and probes for studying biological processes and protein interactions.
• Agrochemical Research: Acts as an intermediate in the development of new crop protection agents and herbicides.

Basic Information

Product Name	Benzenepropanoic Acid, 4-Ethynyl-
CAS No.	880081-84-5
Molecular Formula	C11H10O2
Molecular Weight	174.20 g/mol
Synonyms	4-Ethynylbenzenepropanoic Acid; 3-(4-Ethynylphenyl)propanoic Acid; 4-Ethynylhydrocinnamic Acid; 3-(4-Ethynylphenyl)propionic Acid; (4-Ethynylphenyl)propanoic Acid; Benzenepropanoic acid, 4-ethynyl-; 880081-84-5; 4-Ethynylphenylpropionic acid
EINECS	Contact for details

Quality Control

Our Benzenepropanoic Acid, 4-Ethynyl- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO 9001 standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.