Description

7-Aminoflunitrazepam-D7 is a deuterated analog of the primary metabolite of flunitrazepam, specifically designed for use as an internal standard in analytical chemistry. This compound is critical for ensuring the accuracy and reliability of quantitative analyses in forensic and clinical toxicology. It is primarily utilized by analytical laboratories, pharmaceutical researchers, and forensic scientists for method development and validation in mass spectrometry-based assays.

Application

• Internal Standard for LC-MS/MS: Essential for the precise quantification of 7-aminofunitrazepam and related benzodiazepines in complex biological matrices like blood, urine, and hair.
• Forensic Toxicology: Used in the development and routine application of confirmatory methods for drug-facilitated crime investigations and post-mortem analyses.
• Clinical Research: Supports pharmacokinetic and metabolism studies of benzodiazepines, enabling accurate tracking of drug levels.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of metabolite impurities in drug substance and product testing.
• Reference Material: Serves as a high-purity certified reference material (CRM) for calibrating analytical instruments and validating test methods.
• Regulatory Compliance Testing: Facilitates testing compliant with guidelines from agencies like the FDA and EMA for bioanalytical method validation.

Basic Information

Item	Detail
Product Name	7-Aminoflunitrazepam-D7
CAS No.	879894-27-6
Molecular Formula	C16H5D7FN4O3
Molecular Weight	328.35 g/mol
Synonyms	7-Amino-5-(2-fluorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one-D7; Flunitrazepam D7 Metabolite; 7-Aminofunitrazepam-d7; 7-AFN-D7; 7-Aminofunitrazepam (D7); 1-Methyl-7-amino-5-(o-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one-D7; Deuterated 7-Aminofunitrazepam
EINECS	Contact for details

Quality Control

Every batch of 7-Aminoflunitrazepam-D7 is manufactured and tested under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, supported by comprehensive analytical data including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (typically ≥98% by HPLC), isotopic purity (≥99 atom % D), and conformity to customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccant and inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 99 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.