Description

(1E)-8-Ethyl-4,4,6-Trimethyl-4H-Pyrrolo[3,2,1-Ij]-Quinoline-1,2-Dione 1-Thiosemicarbazone is a specialized heterocyclic organic compound featuring a quinoline core fused with a pyrrole ring and a thiosemicarbazone functional group. This unique molecular architecture makes it a valuable advanced intermediate or research chemical for the development of novel pharmaceuticals and agrochemicals. It is primarily sought by R&D laboratories and fine chemical manufacturers engaged in medicinal chemistry, chemical biology, and material science projects.

Application

• Pharmaceutical Research & Development: Serves as a key synthetic intermediate or a pharmacophore scaffold in the discovery of new drug candidates, particularly for targeting specific enzymes or receptors.
• Medicinal Chemistry Studies: Used to explore structure-activity relationships (SAR) due to its complex fused-ring system and metal-chelating thiosemicarbazone moiety.
• Chemical Biology Probes: Potential utility in developing molecular probes for studying biological processes, given its ability to interact with metal ions in biological systems.
• Agrochemical Intermediate: Acts as a precursor in the synthesis of novel compounds with potential herbicidal, fungicidal, or insecticidal activity.
• Material Science Research: Investigated for its potential in creating organic electronic materials or metal-organic frameworks (MOFs) due to its conjugated structure.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	(1E)-8-Ethyl-4,4,6-Trimethyl-4H-Pyrrolo[3,2,1-Ij]-Quinoline-1,2-Dione 1-Thiosemicarbazone
CAS No.	879617-01-3
Molecular Formula	C19H20N4O2S
Molecular Weight	368.45 g/mol
Synonyms	8-Ethyl-4,4,6-trimethyl-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione 1-thiosemicarbazone; (1E)-8-Ethyl-4,4,6-trimethyl-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione thiosemicarbazone; 4H-Pyrrolo[3,2,1-ij]quinoline-1,2-dione, 8-ethyl-4,4,6-trimethyl-, 1-thiosemicarbazone, (1E)-; Thiosemicarbazone derivative of pyrroloquinoline dione; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of (1E)-8-Ethyl-4,4,6-Trimethyl-4H-Pyrrolo[3,2,1-Ij]-Quinoline-1,2-Dione 1-Thiosemicarbazone adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Research Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.