Description

4-Bromo-6,7-Dimethoxycinnoline is a high-purity, functionalized cinnoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile brominated aromatic scaffold for cross-coupling reactions and further functionalization, enabling the rapid construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other biological pathways where the cinnoline core is pharmacologically relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that incorporate halogenated heterocyclic structures.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry to create tool compounds for studying enzyme function or protein-ligand interactions.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce diverse aryl, heteroaryl, or amino groups.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	4-Bromo-6,7-Dimethoxycinnoline
CAS No.	879014-17-2
Molecular Formula	C10H9BrN2O2
Molecular Weight	269.10 g/mol
Synonyms	4-Bromo-6,7-dimethoxycinnoline; 6,7-Dimethoxy-4-bromocinnoline; Cinnoline, 4-bromo-6,7-dimethoxy-; 879014-17-2; 4-Bromo-6,7-dimethoxy-1,2-diazanaphthalene
EINECS	Contact for details

Quality Control

Our 4-Bromo-6,7-Dimethoxycinnoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability, consistency, and reliability for your critical synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.