Description

3-(2-Fluorophenyl)-5-Methyl-4,5-Dihydroisoxazole-5-Carboxylic Acid (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate characterized by its specific isoxazoline carboxylic acid structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought by pharmaceutical manufacturers, contract research organizations (CROs), and fine chemical suppliers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring the isoxazoline pharmacophore.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• API Synthesis: Serves as a precursor in multi-step synthetic routes for the production of potential Active Pharmaceutical Ingredients.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and herbicides.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploratory synthetic chemistry projects.

Basic Information

Product Name	3-(2-Fluorophenyl)-5-Methyl-4,5-Dihydroisoxazole-5-Carboxylic Acid (Saltdata: Free)
CAS No.	878427-02-2
Molecular Formula	C12H12FNO3
Molecular Weight	237.23 g/mol
Synonyms	5-Methyl-3-(2-fluorophenyl)-4,5-dihydroisoxazole-5-carboxylic acid; 3-(2-Fluorophenyl)-5-methyl-4,5-dihydro-1,2-oxazole-5-carboxylic acid; 5-Methyl-3-(o-fluorophenyl)-4,5-dihydroisoxazole-5-carboxylic acid; 878427-02-2; 3-(2-Fluorophenyl)-5-methyl-2-isoxazoline-5-carboxylic acid; Isoxazoline-5-carboxylic acid derivative; Fluorophenyl dihydroisoxazole carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-(2-Fluorophenyl)-5-Methyl-4,5-Dihydroisoxazole-5-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.