Description

4-Bromo-1-(2-Chloroethoxy)-2-Methoxybenzene is a high-purity, synthetically valuable halogenated aromatic ether. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with complex ether and aryl halide functionalities.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides that require specific halogenated aromatic cores.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, exploring new etherification and halogenation pathways.

Basic Information

Product Name	4-Bromo-1-(2-Chloroethoxy)-2-Methoxybenzene
CAS No.	877399-30-9
Molecular Formula	C9H10BrClO2
Molecular Weight	265.53 g/mol
Synonyms	1-Bromo-4-(2-chloroethoxy)-3-methoxybenzene; 2-Chloroethyl 4-Bromo-3-methoxyphenyl Ether; 4-Bromo-3-methoxyphenyl 2-chloroethyl ether; 2-(4-Bromo-3-methoxyphenoxy)ethyl chloride; 877399-30-9
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-(2-Chloroethoxy)-2-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.