Description

2-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo[3,2-C]Pyridine is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for enabling complex molecular transformations in medicinal chemistry and materials science research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns for constructing complex, drug-like scaffolds via cross-coupling and functionalization reactions.
• Agrochemical Development: Serves as a building block for novel crop protection agents and herbicides, leveraging its unique fused pyrrolopyridine core.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive iodo substituent.
• Material Science Precursor: Potential use in the development of organic electronic materials and photoactive compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for client projects.

Basic Information

Product Name	2-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo[3,2-C]Pyridine
CAS No.	877060-44-1
Molecular Formula	C15H9IN2O2S
Molecular Weight	424.21 g/mol
Synonyms	1H-Pyrrolo[3,2-c]pyridine, 2-iodo-1-(phenylsulfonyl)-; 2-Iodo-1-(benzenesulfonyl)-1H-pyrrolo[3,2-c]pyridine; 1-(Phenylsulfonyl)-2-iodo-1H-pyrrolo[3,2-c]pyridine; 877060-44-1; AI3-52750; SCHEMBL218466; ZINC000095915996; AKOS040759977
EINECS	Contact for details

Quality Control

Our 2-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo[3,2-C]Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with lot-specific data are provided to guarantee it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.