Description

(R)-1-Benzyl-3-Aminopiperidine Dihydrochloride is a high-purity chiral piperidine derivative, serving as a critical building block in advanced pharmaceutical synthesis. Its primary value lies in its role as a key intermediate for the development of active pharmaceutical ingredients (APIs) and other biologically active compounds, particularly those targeting the central nervous system. This compound is essential for research and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors requiring enantiomerically pure intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a ligand or catalyst component in stereoselective chemical reactions to produce enantiomerically pure products.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Neurological & Psychiatric Drug Development: Particularly relevant for compounds targeting receptors and enzymes within the central nervous system.
• Process Chemistry & Scale-up: Employed in the development and optimization of commercial-scale manufacturing routes for pharmaceuticals.
• Fine Chemical Synthesis: Used in the preparation of complex, high-value specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	(R)-1-Benzyl-3-Aminopiperidine Dihydrochloride
CAS No.	876160-18-8
Molecular Formula	C12H20Cl2N2
Molecular Weight	263.21 g/mol
Synonyms	(R)-1-Benzylpiperidin-3-amine dihydrochloride; (3R)-1-Benzyl-3-piperidinamine dihydrochloride; (R)-1-Benzyl-3-piperidinamine dihydrochloride; (R)-3-Amino-1-benzylpiperidine dihydrochloride; (R)-1-Benzyl-3-aminopiperidine HCl; (R)-N-Benzyl-3-aminopiperidine dihydrochloride; (R)-1-Bn-3-NH2-piperidine·2HCl
EINECS	Contact for details

Quality Control

Our (R)-1-Benzyl-3-Aminopiperidine Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the stringent requirements of pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.