Description

4-Chlorothieno[3,2-D]Pyrimidine-6-Carbonitrile is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its role as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. Pharmaceutical R&D teams and fine chemical manufacturers need this precise chemical scaffold to construct complex molecules targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating chemical probes to study enzyme function and cellular pathways.
• Material Science Research: Investigated as a precursor for organic electronic materials due to its fused heterocyclic structure.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for novel heterocyclic chemistry and medicinal chemistry projects.

Basic Information

Product Name	4-Chlorothieno[3,2-D]Pyrimidine-6-Carbonitrile
CAS No.	875798-54-2
Molecular Formula	C7H2ClN3S
Molecular Weight	195.63 g/mol
Synonyms	4-Chlorothieno[3,2-d]pyrimidine-6-carbonitrile; 6-Cyano-4-chlorothieno[3,2-d]pyrimidine; Thieno[3,2-d]pyrimidine-6-carbonitrile, 4-chloro-; 4-Chloro-6-cyanothieno[3,2-d]pyrimidine; 4-Chlorothienopyrimidine-6-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Chlorothieno[3,2-D]Pyrimidine-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and stored away from direct light and moisture sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.