Description

3,4-Difluorophenylhydrazine Hydrochloride is a high-purity, functionalized aromatic hydrazine salt that serves as a critical building block in advanced organic synthesis. Its value lies in providing a reactive hydrazine moiety flanked by fluorine substituents, enabling precise molecular construction for complex heterocycles and active pharmaceutical ingredients. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used to construct pyrazole, triazole, and other nitrogen-containing heterocycles found in modern herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of fluorinated polymers, liquid crystals, and organic electronic materials where fluorine atoms tune electronic properties and stability.
• Chemical Biology Probes: Useful for synthesizing fluorinated hydrazone-based probes and tags for labeling and studying biological systems.

Basic Information

Product Name	3,4-Difluorophenylhydrazine Hydrochloride
CAS No.	875664-54-3
Molecular Formula	C6H5F2N2·HCl
Molecular Weight	194.58 g/mol
Synonyms	(3,4-Difluorophenyl)hydrazine hydrochloride; 1-(3,4-Difluorophenyl)hydrazine hydrochloride; 3,4-DFPH·HCl; Hydrazine, (3,4-difluorophenyl)-, hydrochloride; 3,4-Difluoro-phenyl-hydrazine HCl
EINECS	Contact for details

Quality Control

Our 3,4-Difluorophenylhydrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.