Description

n-(5,6-Dichloro-1,4-Dihydro-2-Quinazolinyl)-2,3-Dihydroxypropanamide 2,2,2-Trifluoroacetate (1:1) is a high-purity synthetic organic compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block or intermediate for the synthesis of novel, biologically active molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in drug discovery programs, particularly those targeting complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazoline-based drug candidates for therapeutic applications.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Potential use in developing enzyme inhibitors or receptor modulators for biological pathway investigation.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures with specific chirality or functionality.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	n-(5,6-Dichloro-1,4-Dihydro-2-Quinazolinyl)-2,3-Dihydroxypropanamide 2,2,2-Trifluoroacetate (1:1)
CAS No.	875467-42-8
Molecular Formula	C₁₃H₁₂Cl₂F₃N₃O₅
Molecular Weight	430.15 g/mol
Synonyms	5,6-Dichloro-2-[(2,3-dihydroxy-1-oxopropyl)amino]-1,4-dihydro-4-quinazolinyl 2,2,2-trifluoroacetate; 2,3-Dihydroxy-N-(5,6-dichloro-1,4-dihydro-2-quinazolinyl)propanamide trifluoroacetate; 875467-42-8; TFA salt of n-(5,6-Dichloro-1,4-dihydro-2-quinazolinyl)-2,3-dihydroxypropanamide; Propanamide, N-(5,6-dichloro-1,4-dihydro-2-quinazolinyl)-2,3-dihydroxy-, 2,2,2-trifluoroacetate (1:1)
EINECS	Contact for details

Quality Control

Our n-(5,6-Dichloro-1,4-Dihydro-2-Quinazolinyl)-2,3-Dihydroxypropanamide 2,2,2-Trifluoroacetate (1:1) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.