Description

Dimethyl Lithospermate B is a high-purity, semi-synthetic derivative of the bioactive natural compound Lithospermate B. This compound is valued for its enhanced stability and bioavailability compared to its parent molecule, making it a critical intermediate for advanced research and development. It is primarily sought by pharmaceutical, nutraceutical, and advanced material research sectors for its potential application in developing novel therapeutic agents and functional ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates targeting oxidative stress and inflammatory pathways.
• Biomedical Research: Used as a reference standard and active agent in in vitro and in vivo studies investigating cardioprotective, neuroprotective, and antioxidant mechanisms.
• Nutraceutical Development: Incorporated into high-end supplement formulations aimed at promoting vascular health and cellular longevity.
• Cosmeceutical Actives: Employed in the development of advanced skincare products for its potential anti-aging and protective properties against environmental stressors.
• Chemical Synthesis: Acts as a versatile precursor for further chemical modification to create libraries of analogs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Dimethyl Lithospermate B
CAS No.	875313-64-7
Molecular Formula	C₃₈H₃₈O₁₈
Molecular Weight	782.70 g/mol
Synonyms	Dimethyl Lithospermate B; Methyl Lithospermate B Dimethyl Ester; 3,4-Bis[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1,5-pentanediyl (2R)-3-(3,4-dihydroxyphenyl)-2-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]propanoate dimethyl ester; Lithospermate B Dimethyl Ester; Salvia miltiorrhiza Derivative
EINECS	Contact for details

Quality Control

Our Dimethyl Lithospermate B is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the material may be stored at 2-8°C. The compound is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.