Description

5'-Bromospiro[Cyclopropane-1,3'-Indolin]-2'-One is a high-value brominated spirocyclic oxindole building block. This compound is of significant interest in advanced organic synthesis, particularly for constructing complex molecular architectures with potential biological activity. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel small molecule therapeutics, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of new crop protection agents and pesticides, leveraging its spirocyclic structure.
• Chemical Biology Probe: Serves as a core scaffold for developing tool compounds to study biological pathways and protein functions.
• Organic Synthesis Building Block: Employed in complex molecule construction, including in cycloaddition reactions and as a precursor for further functionalization.
• Material Science Research: Potential precursor for specialty chemicals and advanced organic materials due to its rigid, three-dimensional structure.

Basic Information

Product Name	5'-Bromospiro[Cyclopropane-1,3'-Indolin]-2'-One
CAS No.	875071-97-9
Molecular Formula	C10H8BrNO
Molecular Weight	238.08 g/mol
Synonyms	5'-Bromo-1'H-spiro[cyclopropane-1,3'-indolin]-2'-one; 5'-Bromospiro[cyclopropane-1,3'-indolin]-2'-one; 2'-Oxo-5'-bromo-1'H-spiro[cyclopropane-1,3'-indoline]; 5'-Bromo-2-oxospiro[cyclopropane-1,3'-indoline]; 875071-97-9; Spiro[cyclopropane-1,3'-indolin]-2'-one, 5'-bromo-
EINECS	Contact for details

Quality Control

Our 5'-Bromospiro[Cyclopropane-1,3'-Indolin]-2'-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.