Description

4-Amino-6-Trifluoromethoxyquinoline is a high-value, multi-functional quinoline derivative distinguished by its trifluoromethoxy and amino substituents. This compound is a critical advanced intermediate in the synthesis of complex molecules, offering unique electronic and steric properties that are difficult to achieve with other functional groups. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of next-generation pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers, organic semiconductors, and liquid crystals.
• Chemical Synthesis Reagent: Employed in organic chemistry research for constructing complex heterocyclic systems and as a ligand in catalytic processes.
• Fluorescent Probe Development: The quinoline core makes it a candidate for developing sensors and imaging agents in biochemical research.

Basic Information

Item	Detail
Product Name	4-Amino-6-Trifluoromethoxyquinoline
CAS No.	874880-25-8
Molecular Formula	C₁₀H₇F₃N₂O
Molecular Weight	228.17 g/mol
Synonyms	6-(Trifluoromethoxy)quinolin-4-amine; 4-Amino-6-(trifluoromethoxy)quinoline; 4-Amino-6-trifluoromethoxyquinoline; Quinoline, 4-amino-6-(trifluoromethoxy)-; 6-Trifluoromethoxyquinolin-4-ylamine
EINECS	Contact for details

Quality Control

Our 4-Amino-6-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.