Description

4-Amino-8-Trifluoromethoxyquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline scaffold substituted with amino and trifluoromethoxy functional groups. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the quinoline structure.
• Organic Synthesis: Serves as a versatile precursor for creating complex molecules in academic and industrial research laboratories.
• Material Science: Investigated for use in the development of organic electronic materials and fluorescent dyes.
• Chemical Reference Standard: Employed as an analytical standard in quality control and method development for regulatory and research purposes.

Basic Information

Product Name	4-Amino-8-Trifluoromethoxyquinoline
CAS No.	874880-24-7
Molecular Formula	C10H7F3N2O
Molecular Weight	228.17 g/mol
Synonyms	8-(Trifluoromethoxy)quinolin-4-amine; 4-Amino-8-(trifluoromethoxy)quinoline; Quinoline, 4-amino-8-(trifluoromethoxy)-; 4-Amino-8-trifluoromethoxy-quinoline
EINECS	Contact for details

Quality Control

Our 4-Amino-8-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.