Description

4-Amino-5,8-Difluoroquinoline is a high-purity, multi-functional quinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of novel fluoroquinolone antibiotics and other bioactive molecules. It is essential for research chemists and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for complex molecular construction.

Application

• Pharmaceutical Intermediate: A crucial precursor for the synthesis of novel fluoroquinolone antibiotic candidates and other nitrogen-containing heterocyclic drugs.
• Agrochemical Research: Used in developing new pesticides and herbicides, leveraging the biological activity of the quinoline scaffold.
• Material Science: Serves as a building block for creating functionalized organic ligands and complex molecules used in organic electronics and catalysis.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex molecular architectures via its reactive amino and halogen sites.
• Dye & Pigment Industry: Acts as an intermediate in the synthesis of specialized fluorinated quinoline-based dyes and colorants.

Basic Information

Product Name	4-Amino-5,8-Difluoroquinoline
CAS No.	874818-15-2
Molecular Formula	C9H6F2N2
Molecular Weight	180.16 g/mol
Synonyms	5,8-Difluoro-4-quinolinamine; 4-Amino-5,8-difluoroquinoline; 5,8-Difluoroquinolin-4-amine; 874818-15-2; Quinoline, 4-amino-5,8-difluoro-; 4-Quinolinamine, 5,8-difluoro-
EINECS	Contact for details

Quality Control

Our 4-Amino-5,8-Difluoroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.