Description

5,8-Difluoro-Quinolin-4-Ol is a high-purity fluorinated quinoline derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where its unique difluoro-quinoline scaffold imparts desirable biological activity and metabolic stability. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, anti-infectives, and oncology.
• Agrochemical Research: Serves as a core structure for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profile.
• Material Science: Used in the research and production of advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and electron-transport layers.
• Chemical Synthesis: A versatile fluorinated building block for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Ligand & Catalyst Development: Employed in the design of novel ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.

Basic Information

Product Name	5,8-Difluoro-Quinolin-4-Ol
CAS No.	874781-10-9
Molecular Formula	C9H5F2NO
Molecular Weight	181.14 g/mol
Synonyms	4-Hydroxy-5,8-difluoroquinoline; 5,8-Difluoro-4-hydroxyquinoline; 5,8-Difluoroquinolin-4-ol; 4-Quinolinol, 5,8-difluoro-; 5,8-Difluoro-4-quinolinol
EINECS	Contact for details

Quality Control

Our 5,8-Difluoro-Quinolin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.