Description

(6Ar,10Ar)-6A,7,10,10A-Tetrahydro-3-[5-(1H-Imidazol-1-Yl)-1,1-Dimethylpentyl]-6,6,9-Trimethyl-6H-Dibenzo[B,D]Pyran-1-Ol Hydrochloride is a high-purity synthetic cannabinoid receptor ligand, a critical intermediate for advanced pharmaceutical research and development. Its value lies in providing researchers with a well-characterized, reliable reference standard for studying the endocannabinoid system and developing novel therapeutics. This compound is essential for pharmaceutical companies, contract research organizations (CROs), and academic institutions focused on neurology, pain management, and metabolic disorder research.

Application

• Pharmaceutical Reference Standard: Serves as a certified analytical standard for method development, validation, and quality control in API synthesis.
• Preclinical Research: Used as a key pharmacological tool in in vitro and in vivo studies to investigate cannabinoid receptor (CB1/CB2) binding affinity, selectivity, and functional activity.
• Drug Discovery & Development: Acts as a crucial intermediate or lead compound in the synthesis of novel therapeutic agents targeting pain, inflammation, appetite regulation, and neurological conditions.
• Metabolite Studies: Employed in the identification and quantification of metabolites for pharmacokinetic and toxicological profiling.
• Biochemical Assay Development: Utilized in high-throughput screening (HTS) campaigns to discover new modulators of the endocannabinoid system.

Basic Information

Product Name	(6Ar,10Ar)-6A,7,10,10A-Tetrahydro-3-[5-(1H-Imidazol-1-Yl)-1,1-Dimethylpentyl]-6,6,9-Trimethyl-6H-Dibenzo[B,D]Pyran-1-Ol Hydrochloride
CAS No.	874745-42-3
Molecular Formula	C27H39ClN2O2
Molecular Weight	459.07 g/mol
Synonyms	JWH-018 N-(5-Chloropentyl) Analog; JWH-018 5'-Chloropentyl Analog; 1-Pentyl-3-(1-naphthoyl)indole 5'-Chloro Analog; AM-678 5'-Chloropentyl; [1-[(1E)-1-Penten-1-yl]-1H-indol-3-yl]-1-naphthalenyl-methanone 5'-Chloro Derivative
EINECS	Contact for details

Quality Control

Every batch of our (6Ar,10Ar)-6A,7,10,10A-Tetrahydro-3-[5-(1H-Imidazol-1-Yl)-1,1-Dimethylpentyl]-6,6,9-Trimethyl-6H-Dibenzo[B,D]Pyran-1-Ol Hydrochloride is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for research-grade chemicals. Certificates of Analysis (COA) detailing HPLC purity, NMR confirmation, and other critical parameters are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.