Description

6-Azaspiro[2.5]Octane-1-Carboxylic Acid Methyl Ester Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical manufacturing seeking to develop new therapeutic agents with complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing complex spirocyclic and bridged heterocycles in drug discovery programs.
• Process Chemistry & Scale-up: Serves as a starting material for the development and optimization of commercial-scale API manufacturing processes.
• Biochemical Tool Compound: Employed in the development of probes and ligands for studying biological targets and pathways.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing of specialized organic molecules.

Basic Information

Product Name	6-Azaspiro[2.5]Octane-1-Carboxylic Acid Methyl Ester Hydrochloride
CAS No.	874365-30-7
Molecular Formula	C9H16ClNO2
Molecular Weight	205.68 g/mol
Synonyms	Methyl 6-azaspiro[2.5]octane-1-carboxylate hydrochloride; 1-Carbomethoxy-6-azaspiro[2.5]octane hydrochloride; 6-Azaspiro[2.5]octane-1-carboxylic acid, methyl ester, hydrochloride; Azaspirooctane carboxylate ester HCl; Spiro[cyclopropane-1,1'-pyrrolidine]-3'-carboxylic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Azaspiro[2.5]Octane-1-Carboxylic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.