Description

2-(4-Trifluoromethylphenyl)Pyridine 1-Oxide is a high-value, organofluorine heterocyclic compound characterized by its pyridine N-oxide core and trifluoromethylphenyl substituent. This structure makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a building block for creating novel ligands in transition metal catalysis and organocatalysis, useful in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and charge-transport materials.
• Fluorine Chemistry Studies: Acts as a model compound for studying the effects of fluorine substitution on the reactivity and physical properties of aromatic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	2-(4-Trifluoromethylphenyl)Pyridine 1-Oxide
CAS No.	874271-40-6
Molecular Formula	C12H8F3NO
Molecular Weight	239.19 g/mol
Synonyms	2-[4-(Trifluoromethyl)phenyl]pyridine 1-oxide; 2-(4-Trifluoromethylphenyl)pyridine N-oxide; 2-(α,α,α-Trifluoro-p-tolyl)pyridine 1-oxide; 4-(Pyridin-2-yl)benzotrifluoride 1-oxide; Pyridine, 2-[4-(trifluoromethyl)phenyl]-, 1-oxide; 874271-40-6; 2-(4-Trifluoromethylphenyl)pyridine oxide
EINECS	Contact for details

Quality Control

Our 2-(4-Trifluoromethylphenyl)Pyridine 1-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.