Description

6-Acetyl-4-Hydroxy-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a defined quinoline core structure. This compound matters for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing novel therapeutic agents, including potential kinase inhibitors and antimicrobials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and anti-infective agents.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Serves as a building block for creating complex, functionalized heterocyclic compounds in custom synthesis and process development.
• Academic & Institutional R&D: Employed in chemical biology and organic synthesis research to explore new reaction pathways and bioactive compound libraries.
• Agrochemical Intermediates: Potential use in the development of new crop protection agents and pesticides based on the quinoline structure.
• Material Science Precursor: Can be utilized in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional materials.

Basic Information

Product Name	6-Acetyl-4-Hydroxy-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	873969-87-0
Molecular Formula	C₁₅H₁₅NO₄
Molecular Weight	273.28 g/mol
Synonyms	Ethyl 6-Acetyl-4-hydroxyquinoline-3-carboxylate; 4-Hydroxy-6-acetyl-3-quinolinecarboxylic Acid Ethyl Ester; 6-Acetyl-4-hydroxy-3-quinolinecarboxylic Acid Ethyl Ester; 6-Acetyl-4-hydroxyquinoline-3-carboxylic acid ethyl ester; 873969-87-0; Ethyl 6-acetyl-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1,4-Dihydro-6-acetyl-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 6-Acetyl-4-Hydroxy-Quinoline-3-Carboxylic Acid Ethyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.