Description

3-Iodomandelic Acid is a versatile iodinated aromatic compound that serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and an iodine substituent on a chiral center, makes it invaluable for constructing complex molecules with high stereochemical fidelity. This compound is primarily sought after by research institutions and pharmaceutical developers for applications in medicinal chemistry, including the synthesis of potential drug candidates and chiral ligands.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) and bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of novel therapeutic agents.
• Asymmetric Synthesis: Employed as a chiral resolving agent or building block for constructing enantiomerically pure compounds.
• Chemical Biology Probes: Utilized in the development of molecular probes and labeled compounds for biochemical studies.
• Organic Synthesis: Serves as a substrate for cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive iodine atom.
• Academic & Industrial R&D: Fundamental reagent in exploratory chemistry for developing new synthetic methodologies.

Basic Information

Product Name	3-Iodomandelic Acid
CAS No.	873963-87-2
Molecular Formula	C8H7IO3
Molecular Weight	278.04 g/mol
Synonyms	(R/S)-3-Iodomandelic Acid; 2-Hydroxy-2-(3-iodophenyl)acetic Acid; α-Hydroxy-3-iodobenzeneacetic Acid; 3-Iodophenylglycolic Acid; 3-Iodo-α-hydroxyphenylacetic Acid; DL-3-Iodomandelic Acid; (±)-3-Iodomandelic Acid; Mandelic acid, 3-iodo-
EINECS	Contact for details

Quality Control

Our 3-Iodomandelic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.