Description

2-(Chloromethyl)-3-(4-Fluorophenyl)Quinazolin-4(3H)-One is a high-value, fluorinated quinazolinone derivative, a key synthetic intermediate prized for its versatile chemical reactivity. This compound is critical for research and development in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery and the production of specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the bioactivity of the quinazolinone core.
• Material Science Precursor: Serves as a starting material for creating specialized organic compounds used in electronic materials or liquid crystals.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and fluoroorganic chemistry.
• Chemical Library Synthesis: A valuable reagent for generating diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	2-(Chloromethyl)-3-(4-Fluorophenyl)Quinazolin-4(3H)-One
CAS No.	873208-55-0
Molecular Formula	C15H10ClFN2O
Molecular Weight	288.70 g/mol
Synonyms	3-(4-Fluorophenyl)-2-(chloromethyl)-4(3H)-quinazolinone; 2-(Chloromethyl)-3-(4-fluorophenyl)-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 2-(chloromethyl)-3-(4-fluorophenyl)-; 873208-55-0; Quinazolin-4(3H)-one, 2-(chloromethyl)-3-(4-fluorophenyl)-; 2-Chloromethyl-3-(4-fluorophenyl)quinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our production of 2-(Chloromethyl)-3-(4-Fluorophenyl)Quinazolin-4(3H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.