Description

7-Amino-4,4-Dimethyl-3,4- Dihydro-2H-Quinoline-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific quinoline-based molecular framework. This compound is of significant value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in research and development pipelines. It is primarily sought after by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, particularly in medicinal chemistry.
• API Synthesis: Serves as a crucial building block for constructing complex molecular architectures found in potential active pharmaceutical ingredients.
• Chemical Research: Used in academic and industrial R&D laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Process Development: Employed in scaling up and optimizing synthetic routes for pharmaceutical manufacturing under cGMP conditions.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	7-Amino-4,4-Dimethyl-3,4- Dihydro-2H-Quinoline-1-Carboxylic Acid tert-Butyl Ester
CAS No.	873056-12-3
Molecular Formula	C16H22N2O2
Molecular Weight	274.36 g/mol
Synonyms	tert-Butyl 7-amino-4,4-dimethyl-3,4-dihydro-2H-quinoline-1-carboxylate; 7-Amino-4,4-dimethyl-1,2,3,4-tetrahydroquinoline-1-carboxylic acid tert-butyl ester; 1-Boc-7-amino-4,4-dimethyl-1,2,3,4-tetrahydroquinoline; 873056-12-3; 2H-Quinoline-1-carboxylic acid, 7-amino-3,4-dihydro-4,4-dimethyl-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 7-amino-4,4-dimethyl-3,4-dihydro-2H-quinoline-1-carboxylate
EINECS	Contact for details

Quality Control

Our 7-Amino-4,4-Dimethyl-3,4- Dihydro-2H-Quinoline-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.